{"id":638,"date":"2019-01-14T12:11:05","date_gmt":"2019-01-14T12:11:05","guid":{"rendered":"http:\/\/dev.jatstudio.com\/the-project"},"modified":"2024-12-04T20:27:26","modified_gmt":"2024-12-04T19:27:26","slug":"the-project","status":"publish","type":"page","link":"https:\/\/dev.jatstudio.com\/en","title":{"rendered":"The Project"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"638\" class=\"elementor elementor-638 elementor-21\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6b6abdf9 elementor-section-height-min-height elementor-section-items-bottom elementor-section-boxed elementor-section-height-default\" data-id=\"6b6abdf9\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-544bb383\" data-id=\"544bb383\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-2b8b01bf elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2b8b01bf\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-7ad8ecd5\" data-id=\"7ad8ecd5\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1af00b46 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"1af00b46\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-68de956b\" data-id=\"68de956b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-1bb29a5f elementor-widget elementor-widget-text-editor\" data-id=\"1bb29a5f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>In search of innovative therapies for Alzheimer&#8217;s Disease<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-3314586a\" data-id=\"3314586a\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6dc9a2ad elementor-align-center elementor-widget elementor-widget-button\" data-id=\"6dc9a2ad\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-md elementor-animation-buzz-out\" href=\"#home\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon elementor-align-icon-right\">\n\t\t\t\t\t\t\t\t\t<i class=\"fa fa-angle-down\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<span class=\"elementor-button-text\">The Project<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5a848e5e elementor-section-content-top elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"5a848e5e\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-edf1960\" data-id=\"edf1960\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-eaad6bf elementor-widget elementor-widget-menu-anchor\" data-id=\"eaad6bf\" data-element_type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"home\" class=\"elementor-menu-anchor\"><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-95e722f elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"95e722f\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInLeft&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">The Project<\/h1>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2d23291 elementor-widget elementor-widget-text-editor\" data-id=\"2d23291\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Alzheimer&#8217;s disease (AD), the main cause associated with dementia, is the most prevalent neurodegenerative disease (NDD) nowadays, with more than 46 million people affected worldwide. Considering its direct relation with aging, this figure is estimated to surpass the amount of 100 million by year 2050.<\/p>\n<p>AD has a tremendous social impact, due to the loss of life quality and autonomy (both for the patient and their relatives \/ caregivers), and also a huge economic burden for national health systems, currently estimated at 818 billion dollars globally.<\/p>\n<p>Despite all the human and economic effort invested, in the last 15 years no new drugs have been incorporated to the clinical practice for the treatment of AD, and the efficacy of those that are commonly used is not satisfactory.<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-78726e73\" data-id=\"78726e73\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-625a87a elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"625a87a\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInLeft&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">News \/ Events<\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-48277b8 elementor-grid-1 elementor-posts--thumbnail-left elementor-grid-tablet-2 elementor-grid-mobile-1 elementor-widget elementor-widget-posts\" data-id=\"48277b8\" data-element_type=\"widget\" data-settings=\"{&quot;classic_columns&quot;:&quot;1&quot;,&quot;classic_row_gap&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:28,&quot;sizes&quot;:[]},&quot;classic_columns_tablet&quot;:&quot;2&quot;,&quot;classic_columns_mobile&quot;:&quot;1&quot;,&quot;classic_row_gap_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;classic_row_gap_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"posts.classic\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-posts-container elementor-posts elementor-posts--skin-classic elementor-grid\">\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-1436 post type-post status-publish format-standard has-post-thumbnail hentry category-events\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/dev.jatstudio.com\/en\/mdpi-webinar-role-of-nrf2-in-neurodegeneration-novel-molecular-mechanisms-and-therapeutic-approaches\" >\n\t\t\t<div class=\"elementor-post__thumbnail\"><img width=\"768\" height=\"312\" src=\"https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2020\/10\/2228-768x312.jpg\" class=\"attachment-medium_large size-medium_large wp-image-1433\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2020\/10\/2228-768x312.jpg 768w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2020\/10\/2228-300x122.jpg 300w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2020\/10\/2228-1024x416.jpg 1024w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2020\/10\/2228.jpg 1200w\" sizes=\"(max-width: 768px) 100vw, 768px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/dev.jatstudio.com\/en\/mdpi-webinar-role-of-nrf2-in-neurodegeneration-novel-molecular-mechanisms-and-therapeutic-approaches\" >\n\t\t\t\tMDPI webinar &#8211; Role of Nrf2 in Neurodegeneration: Novel Molecular Mechanisms and Therapeutic Approaches\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\tOctober 13, 2020\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>On October 16, the coordinator of the NRF24AD project, Manuela<\/p>\n\t\t<\/div>\n\t\t\t\t\t<a class=\"elementor-post__read-more\" href=\"https:\/\/dev.jatstudio.com\/en\/mdpi-webinar-role-of-nrf2-in-neurodegeneration-novel-molecular-mechanisms-and-therapeutic-approaches\" >\n\t\t\t\tRead More &gt;&gt;\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-1387 post type-post status-publish format-standard has-post-thumbnail hentry category-news\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/dev.jatstudio.com\/en\/interview-with-antonio-cuadrado\" >\n\t\t\t<div class=\"elementor-post__thumbnail\"><img width=\"268\" height=\"268\" src=\"https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2020\/06\/Conociendo-la-UAM.jpg\" class=\"attachment-medium_large size-medium_large wp-image-1385\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2020\/06\/Conociendo-la-UAM.jpg 268w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2020\/06\/Conociendo-la-UAM-150x150.jpg 150w\" sizes=\"(max-width: 268px) 100vw, 268px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/dev.jatstudio.com\/en\/interview-with-antonio-cuadrado\" >\n\t\t\t\tInterview with Antonio Cuadrado\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\tJune 2, 2020\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>&#8220;New therapeutic strategies in neurodegenerative diseases&#8221;, interview with one of<\/p>\n\t\t<\/div>\n\t\t\t\t\t<a class=\"elementor-post__read-more\" href=\"https:\/\/dev.jatstudio.com\/en\/interview-with-antonio-cuadrado\" >\n\t\t\t\tRead More &gt;&gt;\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-1305 post type-post status-publish format-standard has-post-thumbnail hentry category-news\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/dev.jatstudio.com\/en\/doctoral-thesis-sheila-abril\" >\n\t\t\t<div class=\"elementor-post__thumbnail\"><img width=\"768\" height=\"569\" src=\"https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2019\/11\/Tesis-Sheila-Abril-768x569.jpg\" class=\"attachment-medium_large size-medium_large wp-image-1304\" alt=\"\" loading=\"lazy\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/dev.jatstudio.com\/en\/doctoral-thesis-sheila-abril\" >\n\t\t\t\tDoctoral Thesis &#8211; Sheila Abril\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\tNovember 5, 2019\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>We continue increasing the number of doctors in the NRF24AD<\/p>\n\t\t<\/div>\n\t\t\t\t\t<a class=\"elementor-post__read-more\" href=\"https:\/\/dev.jatstudio.com\/en\/doctoral-thesis-sheila-abril\" >\n\t\t\t\tRead More &gt;&gt;\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<\/div>\n\n\n\t\t\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e707ab4 elementor-align-right elementor-mobile-align-center elementor-widget elementor-widget-button\" data-id=\"e707ab4\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-md elementor-animation-buzz-out\" href=\"http:\/\/dev.jatstudio.com\/noticias\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon elementor-align-icon-right\">\n\t\t\t\t\t\t\t\t\t<i class=\"fa fa-angle-right\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<span class=\"elementor-button-text\">See all<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3de8dd19 elementor-section-content-middle elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3de8dd19\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-45775f67\" data-id=\"45775f67\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4e02d269 elementor-widget elementor-widget-heading\" data-id=\"4e02d269\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Why are current medicines failing?<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-68172326 elementor-section-content-top elementor-section-boxed elementor-section-height-default elementor-section-height-default elementor-invisible\" data-id=\"68172326\" data-element_type=\"section\" data-settings=\"{&quot;animation&quot;:&quot;zoomIn&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-1fbce16e\" data-id=\"1fbce16e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-efc33ae elementor-position-top elementor-widget elementor-widget-image-box\" data-id=\"efc33ae\" data-element_type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img width=\"138\" height=\"145\" src=\"https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Icono-jeringilla.png\" class=\"elementor-animation-grow attachment-full size-full wp-image-103\" alt=\"\" loading=\"lazy\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\">The selected targets, mainly focused on reducing amyloid A\u03b2 protein deposits and Tau protein aggregates, have not been adequate. These therapies are directed more to the treatment of the symptoms rather than to the cause of the disease.<\/p><\/div><\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-6b13805b\" data-id=\"6b13805b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7625fb85 elementor-position-top elementor-widget elementor-widget-image-box\" data-id=\"7625fb85\" data-element_type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img width=\"155\" height=\"157\" src=\"https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Icono-Molecula.png\" class=\"elementor-animation-grow attachment-full size-full wp-image-101\" alt=\"\" loading=\"lazy\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\">The physiopathological mechanisms and molecular basis of AD are not well understood, so there are no new therapeutic targets available to design other types of drugs.<\/p><\/div><\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-335f5171\" data-id=\"335f5171\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-42917295 elementor-position-top elementor-widget elementor-widget-image-box\" data-id=\"42917295\" data-element_type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img width=\"157\" height=\"157\" src=\"https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Tubo-ensayo.png\" class=\"elementor-animation-grow attachment-full size-full wp-image-102\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Tubo-ensayo.png 157w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Tubo-ensayo-150x150.png 150w\" sizes=\"(max-width: 157px) 100vw, 157px\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\">There are no good biomarkers that allow early diagnosis and \/ or follow-up of the disease.<\/p><\/div><\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-99ba319 elementor-section-height-min-height elementor-section-boxed elementor-section-height-default\" data-id=\"99ba319\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-cafb7b9\" data-id=\"cafb7b9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-20207027 elementor-invisible elementor-widget elementor-widget-image\" data-id=\"20207027\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInLeft&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"1024\" height=\"1024\" src=\"https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Imagen_1.jpg\" class=\"attachment-full size-full wp-image-29\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Imagen_1.jpg 1024w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Imagen_1-150x150.jpg 150w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Imagen_1-300x300.jpg 300w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Imagen_1-768x768.jpg 768w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Imagen_1-100x100.jpg 100w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-a2f1d92\" data-id=\"a2f1d92\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-335c4707 elementor-widget elementor-widget-text-editor\" data-id=\"335c4707\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>On the other hand, there is increasing evidence of the complex nature of AD, where multiple pathogenic factors are interconnected, such as oxidative stress, low-grade inflammation,<br \/>\nproteinopathy and failures in autophagic systems. Therefore, it is necessary to address the problem from new perspectives, such as, for example, the development of multitarget drugs, capable of regulating simultaneously different molecular, metabolic and cellular processes. We are talking about developing innovative therapies beyond the mere treatment of the symptom.<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2e177c1 elementor-widget elementor-widget-text-editor\" data-id=\"2e177c1\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>In this context, the NRF24AD project aims to identify and develop a new neuroprotective drug for the treatment of AD that promotes the endogenous defenses through the activation of the transcription factor NRF2. By this way we pretend to enhance the capacity of the body to avoid \/ diminish \/ mitigate the appearance of this disease, instead of treating only its consequences.<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f1039a9 elementor-section-height-min-height elementor-section-boxed elementor-section-height-default elementor-section-items-middle elementor-invisible\" data-id=\"f1039a9\" data-element_type=\"section\" data-settings=\"{&quot;animation&quot;:&quot;zoomIn&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-86dc923\" data-id=\"86dc923\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a425716 elementor-widget elementor-widget-heading\" data-id=\"a425716\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Why NRF2?<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bc9e63f elementor-widget elementor-widget-spacer\" data-id=\"bc9e63f\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-514dd68 elementor-widget elementor-widget-text-editor\" data-id=\"514dd68\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>The transcription factor NRF2 (Nuclear Factor (Erythroid-Derived 2) -like 2) regulates the expression of a wide battery of genes involved in cell protection, being a key element of several hemostatic mechanisms that are altered during AD\u2019s first stages:<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5c7a982 elementor-align-center elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"5c7a982\" data-element_type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<i class=\"fa fa-dot-circle-o\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Redox state of the cell.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<i class=\"fa fa-dot-circle-o\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Neuroinflammatory response.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<i class=\"fa fa-dot-circle-o\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Proteostasis and autophagy.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a40572a elementor-invisible elementor-widget elementor-widget-image\" data-id=\"a40572a\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;zoomIn&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"847\" height=\"616\" src=\"https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Infograf\u00eda.png\" class=\"attachment-large size-large wp-image-108\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Infograf\u00eda.png 847w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Infograf\u00eda-300x218.png 300w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Infograf\u00eda-768x559.png 768w\" sizes=\"(max-width: 847px) 100vw, 847px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1a017a4 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1a017a4\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-ca6a974\" data-id=\"ca6a974\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9e2e3fb elementor-invisible elementor-widget elementor-widget-image\" data-id=\"9e2e3fb\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInLeft&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"1024\" height=\"1024\" src=\"https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Imagen_7.jpg\" class=\"attachment-large size-large wp-image-35\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Imagen_7.jpg 1024w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Imagen_7-150x150.jpg 150w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Imagen_7-300x300.jpg 300w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Imagen_7-768x768.jpg 768w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Imagen_7-100x100.jpg 100w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-d85b90a\" data-id=\"d85b90a\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-50abd8e elementor-widget elementor-widget-text-editor\" data-id=\"50abd8e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>The activity of NRF2 is deficient in the presence of AD and decreases with aging. However, there are preclinical evidences that demonstrate the possibility of inducing its activity through pharmacological treatments that stabilize this protein.<\/p>\n<p>Therefore, if we are able to fully understand the mechanisms underpinning the regulation of NRF2, we could modulate the endogenous response of the organism and restore those processes that are altered at early stages of AD.<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8227ebb elementor-section-height-min-height elementor-section-boxed elementor-section-height-default elementor-section-items-middle elementor-invisible\" data-id=\"8227ebb\" data-element_type=\"section\" data-settings=\"{&quot;animation&quot;:&quot;zoomIn&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7b0616c\" data-id=\"7b0616c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-56a5f30 elementor-widget elementor-widget-heading\" data-id=\"56a5f30\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">How are we going to achieve this challenge?<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f1fbb62 elementor-widget elementor-widget-spacer\" data-id=\"f1fbb62\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-183ea0f elementor-widget elementor-widget-text-editor\" data-id=\"183ea0f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>We have managed to gather an excellent team of medical chemists, molecular biologists, pharmacologists and physicians, capable of covering all phases for the development of potentially therapeutic compounds, from their identification and synthesis, to their preclinical validation using in vitro techniques and in vivo murine models. We also have an extensive network of contacts in the clinical and pharmaceutical field that will allow us to transfer the results generated beyond preclinical phases.<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2c95e23 elementor-invisible elementor-widget elementor-widget-image\" data-id=\"2c95e23\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInDown&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"1024\" height=\"255\" src=\"https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/banner-1024x255.png\" class=\"attachment-large size-large wp-image-110\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/banner-1024x255.png 1024w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/banner-300x75.png 300w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/banner-768x192.png 768w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/banner.png 1347w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f278766 elementor-section-height-min-height elementor-section-boxed elementor-section-height-default elementor-section-items-middle\" data-id=\"f278766\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-868fa2e\" data-id=\"868fa2e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-635d500 elementor-widget elementor-widget-heading\" data-id=\"635d500\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Projects NRF24AD are organised in the following phases:<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-514578f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"514578f\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-c71cef8\" data-id=\"c71cef8\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1f0cdc2 elementor-section-height-min-height elementor-section-boxed elementor-section-height-default elementor-section-items-middle\" data-id=\"1f0cdc2\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-86d230b\" data-id=\"86d230b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7d9a67a elementor-invisible elementor-widget elementor-widget-image\" data-id=\"7d9a67a\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;zoomIn&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"1024\" height=\"462\" src=\"https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Infografia-fases-1024x462.png\" class=\"attachment-large size-large wp-image-113\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Infografia-fases-1024x462.png 1024w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Infografia-fases-300x135.png 300w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Infografia-fases-768x347.png 768w, https:\/\/dev.jatstudio.com\/wp-content\/uploads\/2018\/11\/Infografia-fases.png 1570w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>In search of innovative therapies for Alzheimer&#8217;s Disease The Project The Project Alzheimer&#8217;s disease (AD), the main cause associated with dementia, is the most prevalent neurodegenerative disease (NDD) nowadays, with more than 46 million people affected worldwide. Considering its direct relation with aging, this figure is estimated to surpass the amount of 100 million by &#8230; <a title=\"Doctoral Thesis &#8211; Sheila Abril\" class=\"read-more\" href=\"https:\/\/dev.jatstudio.com\/en\/doctoral-thesis-sheila-abril\">Read more <span class=\"screen-reader-text\">Doctoral Thesis &#8211; Sheila Abril<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"acf":[],"_links":{"self":[{"href":"https:\/\/dev.jatstudio.com\/en\/wp-json\/wp\/v2\/pages\/638"}],"collection":[{"href":"https:\/\/dev.jatstudio.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/dev.jatstudio.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/dev.jatstudio.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dev.jatstudio.com\/en\/wp-json\/wp\/v2\/comments?post=638"}],"version-history":[{"count":14,"href":"https:\/\/dev.jatstudio.com\/en\/wp-json\/wp\/v2\/pages\/638\/revisions"}],"predecessor-version":[{"id":4159,"href":"https:\/\/dev.jatstudio.com\/en\/wp-json\/wp\/v2\/pages\/638\/revisions\/4159"}],"wp:attachment":[{"href":"https:\/\/dev.jatstudio.com\/en\/wp-json\/wp\/v2\/media?parent=638"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}